A calmer week three
That tight-wire feeling, where small things feel big and your fuse is gone by noon? Relume is made to support a steadier, calmer mood through the two weeks before your period.*
★★★★★ Rated 4.7 "Excellent" based on 1,129 reviews
Relume Luteal · Daily Cycle Support
A Calmer Cycle Starts Here
Made with clinically studied saffron to help support a calmer cycle, naturally.*
Luteal Mood Support*Calm & Composure*Restful Sleep*Mental Clarity*Cycle Comfort*Cravings Support*
93% Sold
Description
Research-Backed Formula
Built with the same saffron extract used in clinical trials against PMS and PMDD, including the ones that put it head to head with prescription SSRIs, plus passionflower, gotu kola, and ginger, each are studied for what they do to the nervous system and the physical symptoms that show up alongside the mood swings.
✓ Saffron extract standardized to active crocin and safranal, the same compound markers used in the research comparing saffron directly against SSRIs for mood symptoms
✓ Supports serotonin activity during the second half of your cycle, when the hormone that normally buffers serotonin's dip is already falling
✓ Passionflower works on the same GABA pathway targeted by anti anxiety medication, without the sedation or dependence risk that comes with a benzodiazepine
✓ Gotu kola supports healthy circulation and normal fluid balance, the mechanism behind the bloating and physical heaviness that usually shows up right alongside the mood symptoms
✓ Ginger root reduces the prostaglandins responsible for cramping, the same inflammatory compounds an NSAID is targeting when it works
✓ Dosed at the same levels used in the actual clinical research, not a fraction of it hidden inside a proprietary blend
✓ Every batch is third party lab tested, so the amount on the label is the amount in the gummy
✓ No SSRI, no daily antidepressant, nothing that requires a taper if you decide to stop
✓ No synthetic hormones, so nothing new is being introduced to a system that birth control already disrupted once
✓ Built around the luteal phase specifically, so you're not taking a flat daily dose for a symptom that isn't happening yet
✓ Supports steadier mood, calmer sleep, and less physical discomfort during the same two weeks every month, not a vague everyday wellness claim
✓ Formulated for the exact window your psychiatrist told you didn't matter, because the studies say otherwise
What’s in it
Per 2 gummies: Saffr’Activ® saffron extract 30 mg, organic passionflower 150 mg, gotu kola 100 mg, organic ginger 15 mg. 3 g added sugar, 20 calories. Strawberry flavor. Vegan, non-GMO, gluten-free.
How to take it
- Start the day after ovulation (or ~14 days before your expected period).
- Take 2 gummies a day until your period starts.
- One 30-gummy pouch covers one luteal phase (15 days).
- Log mood, sleep and rage days for 3 cycles.
Why “Luteal”?
The luteal phase is the two weeks between ovulation and your period. It’s when many women feel the shift in mood, sleep and patience. The only saffron trial in women with premenstrual dysphoric disorder gave saffron in the luteal phase only.
What's Not Included
✓ No artificial flavors or sweeteners
✓ No preservatives
✓ Non-GMO
✓ Gluten-free
✓ Soy-free
✓ Dairy-free
✓ Sugar-free
✓ No fillers
✓ GMP Certified
Money Back Guarantee
90-Day Money Back Guarantee
Not 100% satisfied? Email us within 90 days for a full refund. No questions asked.
Relume Luteal
Add to cartWhat Relume is made to support
Four things you may notice by your third cycle*
Relume Luteal is taken in the two weeks before your period, when your body asks the most of you. Here is what it is designed to support.
A night that actually rests you
Exhausted, but wide awake at 3 a.m. Saffron and passionflower are traditionally used to support relaxation and restful sleep, so mornings feel a little less like climbing out of a hole.*
Patience you recognize
The snap at the kids. The sigh at your partner. The guilt after. Relume supports emotional steadiness, so the hard days feel less like a minefield and more like you.*
Your own numbers, not guesses
Take two gummies a day, log your bad days in our free tracker, and compare cycle to cycle. After 3 cycles, you decide with your own data, backed by our 90-day guarantee.
30 mg
saffron per day, the dose used in nearly every premenstrual trial
612
women across the 7 studies in the 2025 meta-analysis
2–3
cycles: how long the trials ran, and how long we ask you to track
0
hormones. Nothing added, nothing suppressed
Sources: Mohammadi & Karimi 2025 (KJFM); Rajabi et al. 2020 (Adv Biomed Res).
Why nothing has worked
Your hormone tests came back “normal.” Week three still wrecked you.
That’s not a coincidence, and it’s not a character flaw. In NIH research, women with severe premenstrual mood symptoms had normal hormone levels. The difference was how their brains reacted to normal monthly shifts.
So when “hormone balance” pills missed, and the pill made things worse for some of us, it wasn’t because you failed. They were aimed at the wrong target. You don’t fix sunburn by changing the sun. You protect yourself in the hours it’s strongest.
“That’s an explanation, not an excuse.” You already own your part. Relume is for the part you can’t white-knuckle.
Same sun. Different skin.
Most womenNormal hormone shifts. A little glow.
Hormone-sensitiveSame shifts. Your brain burns.
You’ve already done the hard part
You didn’t fail the fixes. The fixes didn’t fit.
Some of it helped some of us. If something works for you, keep it. If you’re still counting bad days, Relume is one more tool, not another leap of faith.
Birth control
“It made my PMDD a full time thing.”
Helps some women. For others it turned ten bad days into a full-time thing. Adding hormones to a hormone-sensitive brain can feel like roulette.
Relume: hormone-free
SSRIs
“I’d rather dull myself than be volatile with my kids.”
They give many women their life back. For others it’s numbness, side effects, or not wanting a daily pill for a two-week problem.
Relume: ask your prescriber how it fits with yours
The supplement stack
“My Big Bin of Discarded Supplements™.”
Magnesium. B6. Vitex. Drugstore saffron at who-knows-what dose. You couldn’t tell what helped, so you stopped everything.
Relume: one studied dose, one routine, one tracker
The Luteal Protocol
Two weeks. Two gummies a day. Your own numbers.
You already know your cycle day better than most doctors do. Relume runs on that.
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PeriodFollicularOvulationTake 2 gummies/day
1
Start after ovulation
Or about 14 days before your expected period. Irregular cycle? Use an ovulation test or your app.
2
Take 2 a day
Until your period starts. One pouch (30 gummies) covers the whole luteal phase.
3
Count your bad days
Log mood, sleep and rage days with our tracker. Judge it on your own data after 3 cycles.
Example calendar for a 28-day cycle. Your cycle may differ. Not a medical device or a substitute for medical care.
Inside every pouch
One ingredient at the studied dose. Three in support.
Supplement Facts
Serving2 gummies
Servings per pouch15
Calories20
Added sugars3 g
Saffron extract (Saffr’Activ®)30 mg
Passionflower (organic)150 mg
Gotu kola100 mg
Ginger (organic)15 mg
Confirm against the final label. Third-party certificate of analysis: link here.
Saffron (Saffr’Activ®) · 30 mgSTUDIED DOSE
The dose used in nearly every premenstrual saffron trial.
Passionflower · 150 mgSUPPORTING
Traditionally used for calm. Not studied at this exact dose.
Gotu kola · 100 mgSUPPORTING
A traditional botanical. Included at a typical extract amount.
Ginger · 15 mgSUPPORTING
Traditionally paired with premenstrual routines. Well below trial doses.
What to expect
Don’t take our word for it. Count your bad days.
Cycle 1 · Set your baseline
Log your usual bad days. Some women notice small shifts in sleep or evenness. Many notice nothing yet, and that’s normal.
Cycle 2 · Compare
Put your bad-day count next to cycle 1. Trials measured change over 2–3 cycles, so patience is part of the protocol.
Cycle 3 · Decide with your own data
Number dropped? Keep going. Didn’t? Email us before day 90 and we refund every dollar.
Why Relume Luteal
This isn’t a “happy” gummy. It’s a luteal one.
Relume Luteal
Typical mood gummy
Built around the luteal phase
✓
—
Saffron at the studied 30 mg/day
✓
Often ✓
Cycle-timed routine & 3-cycle tracker
✓
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Plain-English medication guidance sheet
✓
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Published certificate of analysis
✓
Rare
Guarantee that covers 3 cycles
90 days
Varies
Contains hormones
No
No
90DAY
Count your bad days. If the number doesn’t drop, you pay nothing.
Most guarantees expire before you can judge anything. Studies ran two to three cycles, so ours covers three. Log your days with our tracker. If your own numbers don’t move, email us within 90 days for a full refund. No guilt, no hoops.
For the person who loves her
Your partner isn’t the enemy in week three. They just don’t have the map.
The free Partner’s Guide to Week Three explains what’s happening, what actually helps, and why “is it that time?” never does. It comes with every 3-cycle subscription.
Questions we’d ask too
Straight answers
Am I about to waste money again?
It might not work for you, and we’d rather say that than hide it. That’s why the guarantee covers three full cycles and comes with a tracker, so you can judge it on your own data.
Is this just placebo?
In trials, saffron beat placebo by a moderate margin, but placebo groups also improved a lot. Most studies are small and from one region. See “Straight talk” above.
Will it clash with my SSRI?
One small 4-week trial of saffron added to SSRIs found no lab-safety problems, but the evidence is thin. Ask your prescriber or pharmacist, and bring our one-page sheet.
How long before I know?
Trials measured change over 2–3 cycles. Some people notice something sooner; many don’t. Give it three cycles and track your bad days.
Could it make me worse?
Most trial participants tolerated saffron like placebo, but some people report feeling worse. If your mood gets worse, stop and talk to your doctor.
Is it hormones?
No. Relume Luteal is hormone-free: it doesn’t add, block or change your hormones.
Can I take it if we’re trying to conceive?
Saffron isn’t recommended during pregnancy, and the luteal phase can overlap with early pregnancy. If you’re trying to conceive, ask your OB first.
Why not just buy cheap saffron capsules?
Saffron capsules can work, and some are good. We use the branded Saffr’Activ® extract at 30 mg per day, publish our certificate of analysis, and add a routine and tracker. We don’t claim it is better for everyone.
My cycle is irregular. Now what?
Use an ovulation test or your tracking app to find ovulation. Start the day after. If you can’t predict it, talk to your doctor first.
Day 21 is coming whether you’re ready or not.
Make it a different one. Hormone-free. Studied-dose saffron. Counted in your own app. Free if your numbers say it didn’t help.
Start my first cycle