Excellent 4.7/5

Relume Hormone Balance Gummies

Two weeks of PMDD rage. Two weeks of apologizing for it. Lume's saffron formula is built to break the cycle.

  • Calms Luteal Phase Rage — supports serotonin during the days before your period
  • Supports Deep Sleep — eases the insomnia that hits hardest before your period
  • Eases Symptoms All Cycle Long — supports mood and cramping in every phase
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Money Back Guarantee

30-Day Money Back Guarantee

That's how confident we are in your results. But if you're not thrilled, send it back and we'll refund your purchase.

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You're not losing your mind. You're losing serotonin.

Serotonin naturally drops during the luteal phase, the two weeks before your period, disrupting the same brain chemistry that keeps your mood, sleep, and emotional reactions steady the rest of the month. 

That drop is what turns a normal day into a short fuse, a crying spell, or a night you can't fall asleep, and it happens on the same schedule every single cycle whether you're ready for it or not.

  • Rage Spikes
  • Crying Spells
  • Luteal Insomnia
  • Lost Control

Results vary. Product benefits are based on ingredient research and consumer-reported experiences.

4 Clinically-Studied Compounds Working Together

Cycle-timed support for the systems that shift the most in your luteal phase.

SAFFRON EXTRACT

SAFFRON EXTRACT

Standardized crocin and safranal for serotonin support.

PASSIONFLOWER

PASSIONFLOWER

GABA support for a calmer, steadier nervous system.

GOTU KOLA

GOTU KOLA

Supports healthy circulation and normal fluid balance.

GINGER ROOT

GINGER ROOT

Reduces the prostaglandins behind cramping.

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Stop buying "expensive" chemicals

If you've tried magnesium, the pill, or an antidepressant and still spend the week before your period feeling like a different person, you're not alone, and it's not your fault.

Birth control can feel like a permanent luteal phase. SSRIs switch off the good feelings along with the bad. And another supplement stack just means more money and more guessing.

Relume is different.

One Ingredient That Works:
30 mg of clinically studied saffron extract, the dose women with PMDD say actually moved the needle. No hormones. No side effects you have to live with.

Built for Your Cycle:
One serving daily. Two during luteal, when the rage, the tears, and the 2am wake ups hit hardest. Give it four to six weeks to build, then get your month back.

For the week you end up apologizing for.

Days 14 Through 28*

You know your cycle day without opening the app. So you take this in the second half, when the switch flips, and skip day 6 when you feel fine anyway.

Fewer Rage Days*

For the text you sent at 11pm and reread the next morning with your stomach dropping. Saffron supports serotonin through the stretch where your fuse runs out by noon.

Every MG On The Label

30mg saffron, 150mg passionflower, 100mg gotu kola, 15mg ginger. All printed right there, so you can check them against the studies like you were going to anyway.

Get Your Month Back

Your partner checks the calendar before bringing anything up. Your kids can tell which week it is. You want a month where nobody has to plan around you.

What Women Typically Notice — Cycle By Cycle

Cycle 1:

Early Settling In

Many women describe a subtle shift within the first cycle. The edge feels a little less sharp, and small annoyances don't spiral as fast as they normally would.

End of Cycle 1

Sleep Shifts First

By the end of the first luteal phase, sleep is usually the first thing that changes, falling asleep faster and waking less during the week she'd normally be up at 3am.

Cycle 2

The Most Common "Turning Point"

This is where most women say the real difference shows up. The rage that used to build out of nowhere takes longer to get there, and when it does, it doesn't hit as hard.

Cycle 3

Patterns Fully Break

By the third cycle, the whole two weeks start to feel more predictable. Fewer blindsided days, fewer moments she doesn't recognize herself in.

★★★★★ 4.7/5 based on 1,245 Total Ratings

FREQUENTLY ASKED QUESTIONS

Does saffron actually work, or is it just hype? +

Saffron is one of the most researched natural ingredients for mood. A 2025 meta-analysis of placebo-controlled trials found saffron significantly improved premenstrual symptom scores compared with placebo. A separate double-blind trial found that 30 mg a day over two cycles improved premenstrual and mood scores more than placebo.

How do I take it? +

Take 1 gummies daily, all month. During the 10 to 14 days before your period, you can increase to 2 gummies a day, taking 2 in the morning and 2 in the evening.

How long until I notice a difference? +

Most studies measured results over two full cycles. Some women notice changes within the first few weeks, but give it at least two cycles before you decide.

Are there side effects? +

Saffron was well tolerated in clinical studies, with minimal side effects reported. Some people may experience mild stomach upset. Do not take Relume if you are pregnant or breastfeeding.

Does it contain hormones? +

No. Relume is completely hormone-free. It supports your mood without changing your reproductive hormones, which makes it a good fit if hormonal birth control didn't work for you.

Will it work for me? +

No supplement works for everyone, and we won't pretend otherwise. Many women find saffron makes a real difference; others notice less. That's why every order comes with a 90-day return policy.

Can I take it with my antidepressant or birth control? +

Talk to your doctor first. Saffron may interact with antidepressants (including SSRIs), sedatives, blood pressure medication and blood thinners.

What's in it? +

Each 2-gummy serving contains 30 mg of clinically studied Saffr'Activ® saffron extract, plus passionflower for calm, gotu kola for mental clarity and ginger for comfort. It's vegan, non-GMO, lab tested and has a natural strawberry flavor.